Altered functional resting-state hypothalamic connectivity and abnormal pituitary morphology in children with Prader-Willi syndrome

Table 2 Hypothalamus and pituitary gland volumes in children with PWS

	PWS				Control
	mUPD		DEL		Control
	Mean	SD	Mean	SD	Mean	SD	p value^a
Hypothalamus	5395.0	1109.5	5542.2	1101.6	5657.3	1349.3	.82
Mammillary bodies	922.8	177.5	788.8	85.7	970.1	168.8	.33
Pituitary gland	1279.4	501.4	1267.3	394.0	2674.6	1057.8	<.0001
Posterior pituitary bright spot	13/13		14/14		28/28
Pituitary stalk length (mm)	7.9	1.9	7.07	2.5	5.6	2.0	.041
Interrupted stalk	0/13		0/14		0/28

Data expressed as mean (SD) or number (mm³) unless indicated otherwise. No significant differences were found in either age or gender distribution between the groups
DEL deletion, mUPD maternal uniparental disomy, PWS Prader-Willi syndrome, SD standard deviation
^aPWS vs. control

ISSN: 1866-1955