Table 1 Characteristics of study subjects
| Â | Neurotypical | Angelman |
|---|---|---|
Total patients | 72 | 28 |
 Age (years) | 7.0 ± 0.2 | 5.8 ± 0.3 |
 Male | 42 (58%) | 14 (50%) |
 Female | 30 (42%) | 14 (50%) |
 Molecular diagnosis | N/A | Class 1 deletion: 7 Class 2 deletion: 10 UBE3A mutation: 6 Atypical deletion: 2 Uniparental disomy: 1 Imprinting defect: 1 Abnormal DNA methylation, negative for deletion: 1 |
 History of seizures | 0 (0%) | 26 (93%) |
Patients with wake in EEG | 54 (75%) | 26 (93%) |
 Age (years) | 6.6 ± 0.3 | 5.8 ± 0.3 |
 Male | 30 (56%) | 14 (54%) |
 Female | 24 (44%) | 12 (46%) |
 Wakeful EEG length (min) | 7.9 ± 1.0 | 18.2 ± 2.3 |
 Seizures under control at time of first recording or no seizure history | 54 (100%) | 24 (92%) |
Patients with sleep in EEG | 54 (75%) | 13 (46%) |
 Age (years) | 7.1 ± 0.3 | 6.0 ± 0.4 |
 Male | 32 (59%) | 8 (62%) |
 Female | 22 (41%) | 5 (38%) |
 Sleep EEG length (min) | 13.6 ± 0.8 | 22.0 ± 2.4 |
 Seizures under control at time of first recording or no seizure history | 54 (100%) | 12 (92%) |