| Breath-holding | Hyperventilation | Both breath-holding and hyperventilation | Abdominal bloating |
---|---|---|---|---|
 | n/N (%) | n/N (%) | n/N (%) | n/N (%) |
Overall | 260/378 (68.8) | 179/386 (46.4) | 158/384 (41.2) | 173/408 (42.4) |
Age group | ||||
 0–6 years | 32/49 (65.3) | 29/48 (60.4) | 27/48 (56.3) | 20/51 (39.2) |
 7–12 years | 99/130 (76.2) | 59/130 (45.4) | 59/130 (45.4) | 48/131 (36.6) |
 13–19 years | 76/113 (67.3) | 48/114 (42.1) | 38/114 (33.3) | 49/121 (40.5) |
 20 years and above | 53/86 (61.6) | 43/94 (45.7) | 34/92 (37.0) | 56/105 (53.3) |
Mutation type | ||||
 C-terminal deletion | 28/41 (68.3) | 17/42 (40.5) | 14/42 (33.3) | 16/44 (36.4) |
 Early truncating | 23/28 (82.1) | 13/27 (48.2) | 13/27 (48.2) | 14/28 (50.0) |
 Large deletion | 21/26 (80.8) | 12/26 (46.2) | 12/26 (46.2) | 12/28 (42.9) |
 p.Arg106Trp | 10/15 (66.7) | 7/15 (46.7) | 4/15 (26.7) | 6/15 (40.0) |
 p.Arg133Cys | 19/29 (65.5) | 15/30 (50.0) | 13/30 (43.3) | 12/30 (40.0) |
 p.Arg168* | 26/40 (65.0) | 19/43 (44.2) | 16/42 (38.1) | 22/44 (50.0) |
 p.Arg255* | 32/44 (72.7) | 22/44 (50.0) | 21/44 (47.7) | 18/46 (39.1) |
 p.Arg270* | 17/24 (70.8) | 11/24 (45.8) | 10/24 (41.7) | 10/25 (40.0) |
 p.Arg294* | 18/27 (66.7) | 12/27 (44.4) | 11/27 (40.7) | 10/29 (34.5) |
 p.Arg306Cys | 18/26 (69.2) | 15/26 (57.7) | 13/25 (52.0) | 11/27 (40.7) |
 p.Thr158Met | 24/34 (70.6) | 18/36 (50.0) | 17/36 (47.2) | 23/43 (53.5) |
 Other | 24/44 (54.6) | 18/46 (39.1) | 14/46 (30.4) | 19/49 (38.4) |