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Fig. 3 | Journal of Neurodevelopmental Disorders

Fig. 3

From: Is dopamine transporter-mediated dopaminergic signaling in the retina a noninvasive biomarker for attention-deficit/ hyperactivity disorder? A study in a novel dopamine transporter variant Val559 transgenic mouse model

Fig. 3

AMPH treatment alters photopic b-wave amplitudes differently in WT vs. DAT Val559 HOM in male mice. AMPH-treated (4 mg/kg) WT (a) (F (1,80) = 12.758, ***P < 0.001, two-way ANOVA, n = 5–7 mice) showed increased light-adapted b-wave amplitudes, but homozygous mutants (b) were not affected by AMPH (F (1,48) = 0.688, P = 0.411, two-way ANOVA, n = 3–5 mice). c The increments of ERG amplitude following AMPH injection were quantified by each genotype (HOM: white bar; WT: black bar) (t = −3.774, **P = 0.002, t test). All data are represented as means ± SEM

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