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Table 3 Median subscale scores of each behavioural measure and associated cross-syndrome comparisons and post hoc tests

From: The behavioural phenotype of Potocki-Lupski syndrome: a cross-syndrome comparison

 

Syndrome group median scores (interquartile range)c

Cross-syndrome comparison

Measures

PTLS

SMS

ASD

p value

Post hoc test

Social Communication Questionnaire

Reciprocal social interaction

4.00 (2.00–7.25)

7.00 (4.00–8.75)

11.00 (8.00–13.00)

< .001

ASD > PTLS, SMS

Communicationa

6.75 (4.66–8.03)

6.00 (3.79–8.00)

9.00 (7.00–11.00)

< .001

ASD > PTLS, SMS

Restricted, repetitive and stereotyped behaviours

5.00 (3.00–7.00)

5.00 (3.00–6.00)

6.00 (4.00–7.50)

.072

 

Repetitive Behaviour Questionnaire

Stereotyped behaviour

4.00 (0.00–8.00)

8.00 (3.00–11.00)

6.00 (2.50–11.50)

.034

 

Compulsive behaviour

12.00 (2.75–15.25)

2.00 (0.00–5.00)

8.00 (3.00–18.00)

< .001

PTLS, ASD > SMS

Insistence on sameness

2.00 (0.00–7.00)

3.00 (1.00–4.00)

5.00 (2.25–8.00)

.014

 

Restricted preferencesa

5.00 (3.50–8.00)

5.00 (4.00–8.00)

4.00 (2.00–8.50)

.814

 

Repetitive speecha

4.00 (2.00–8.00)

6.00 (4.00–9.00)

6.00 (2.00–9.50)

.334

 

Challenging Behaviour Questionnaire

Self-injury severity score

6.50 (4.25–9.00)

7.00 (5.00–9.00)

7.00 (5.00–8.00)

.894

 

Mood, Interest and Pleasure Questionnaire-Short Form

Mood

21.00 (19.00–23.00)

20.00 (17.00–22.00)

18.00 (17.00–21.00)

.092

 

Interest and pleasureb

17.26 (15.65–18.87)

16.25 (14.47–18.02)

13.71 (12.05–15.38)

.008

PTLS > ASD

The Activity Questionnaire

Impulsivity

13.00 (7.75–19.00)

20.00 (16.00–24.00)

19.00 (11.50–21.00)

.002

SMS > PTLS

Overactivity

10.00 (5.50–20.50)

16.00 (9.00–27.00)

20.00 (8.00–29.00)

.090

 

Impulsive speecha

4.00 (1.00–5.00)

5.00 (2.00–9.00)

5.00 (3.00–9.50)

.057

 
  1. aSubscales differ depending on verbal ability. Scores are prorated for non-verbal individuals (SCQ communication) or are not scored for non-verbal individuals, and therefore, the group n differs for these subscales (RBQ restricted preferences, RBQ repetitive speech, TAQ impulsive speech)
  2. bNormally distributed data; therefore, parametric analysis of variance (ANOVA) was conducted (means and 95% confidence intervals reported)
  3. cInterquartile range based on weighted average at 25 and 75 percentiles