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Table 1 Demographics of each group

From: A cross-syndrome cohort comparison of sleep disturbance in children with Smith-Magenis syndrome, Angelman syndrome, autism spectrum disorder and tuberous sclerosis complex

  AS (n = 70) SMS (n = 26) TSC (n = 20) ASD (n = 30) TD (n = 47) χ 2 df p value Post hoc analysis (p < .01)
Mean age (SD) 8.64 (3.77) 8.54 (3.08) 7.20 (4.11) 9.45 (3.47) 8.00 (3.24) 5.66 4 .226
Males (%) 45.7 61.5 55.0 70.0 66.0 7.50 4 .112
Genetic mechanism (%) Deletion 70.0 92.3      
Mutation 7.1 0      
TSC1 15.0      
TSC2 60.0      
UPD 11.4 0      
Imprinting 7.1 0      
Other 1.4 0 5.0      
Translocation 1.4 3.8      
Clinical diagnosis 1.4 0 5.0 100.0      
Unknown 0 3.8 0 0      
Awaiting genetic results 0 0 5.0      
Missing data    10.0       
BMI categorya Overweight (%) 28.9 25.0 26.3 13.0 1.76 4 .779
Speech Verbal (%) 8.6 84.6 80.0 76.7 100 120.88 4 < .001 TD, ASD, TSC; SMS > AS
Mobility Walk unaided (%) 72.9 100 100 96.7 100 41.31 4 < .001 TD, ASD, SMS; TSC > AS
Currently/occasionally using melatonin or other sleep medication (%) 71.4 46.2 30.0 40.0 2.1 53.52 4 < .001 AS > ASD; TSC, ASD, SMS > TD
Symptoms indicative of reflux (%) 67.1b 64.0c 35.0 43.3 9.68 3 .021 AS > ASD, TSC
Seizures last month (%) 62.9 11.5 80.0 3.3 30.21 3 < .001 TSC > ASD, SMS; AS > ASD, SMS
Taking anti-epilepsy medication (%) 70.0 3.8 75.0 0 65.79 3 < .001 TSC > ASD, SMS; AS > SMS, ASD
TAQ impulsivity mean (SD) 15.25b (5.19) 17.92 (2.65) 13.30 (7.17) 15.47 (4.92) 7.28 3 .064
TAQ overactivity mean (SD) 17.40b (9.16) 21.0c (7.25) 16.0 (10.99) 21.57 (15.92) 5.01 3 .171
  1. aData related to 64 children with AS, 15 children with SMS, 19 children with ASD and 18 children with TSC
  2. bData only related to 30 children with AS
  3. cData only related to 25 children with SMS