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Table 1 Demographics of each group

From: A cross-syndrome cohort comparison of sleep disturbance in children with Smith-Magenis syndrome, Angelman syndrome, autism spectrum disorder and tuberous sclerosis complex

 

AS

(n = 70)

SMS

(n = 26)

TSC

(n = 20)

ASD

(n = 30)

TD

(n = 47)

χ 2

df

p value

Post hoc analysis (p < .01)

Mean age

(SD)

8.64

(3.77)

8.54

(3.08)

7.20

(4.11)

9.45

(3.47)

8.00

(3.24)

5.66

4

.226

–

Males (%)

45.7

61.5

55.0

70.0

66.0

7.50

4

.112

–

Genetic mechanism (%)

Deletion

70.0

92.3

–

–

     

Mutation

7.1

0

–

–

     

TSC1

–

–

15.0

–

     

TSC2

–

–

60.0

–

     

UPD

11.4

0

–

–

     

Imprinting

7.1

0

–

–

     

Other

1.4

0

5.0

–

     

Translocation

1.4

3.8

–

–

     

Clinical diagnosis

1.4

0

5.0

100.0

     

Unknown

0

3.8

0

0

     

Awaiting genetic results

0

0

5.0

–

     

Missing data

  

10.0

      

BMI categorya

Overweight (%)

28.9

25.0

26.3

13.0

–

1.76

4

.779

–

Speech

Verbal (%)

8.6

84.6

80.0

76.7

100

120.88

4

< .001

TD, ASD, TSC; SMS > AS

Mobility

Walk unaided (%)

72.9

100

100

96.7

100

41.31

4

< .001

TD, ASD, SMS; TSC > AS

Currently/occasionally using melatonin or other sleep medication (%)

71.4

46.2

30.0

40.0

2.1

53.52

4

< .001

AS > ASD; TSC, ASD, SMS > TD

Symptoms indicative of reflux (%)

67.1b

64.0c

35.0

43.3

–

9.68

3

.021

AS > ASD, TSC

Seizures last month (%)

62.9

11.5

80.0

3.3

–

30.21

3

< .001

TSC > ASD, SMS; AS > ASD, SMS

Taking anti-epilepsy medication (%)

70.0

3.8

75.0

0

–

65.79

3

< .001

TSC > ASD, SMS; AS > SMS, ASD

TAQ impulsivity mean

(SD)

15.25b

(5.19)

17.92

(2.65)

13.30

(7.17)

15.47

(4.92)

–

7.28

3

.064

–

TAQ overactivity mean

(SD)

17.40b

(9.16)

21.0c

(7.25)

16.0

(10.99)

21.57

(15.92)

–

5.01

3

.171

–

  1. aData related to 64 children with AS, 15 children with SMS, 19 children with ASD and 18 children with TSC
  2. bData only related to 30 children with AS
  3. cData only related to 25 children with SMS