From: Neural correlates of socio-emotional perception in 22q11.2 deletion syndrome
Diagnostic group | Comparison | |||||
---|---|---|---|---|---|---|
22q11DS | Controls | ANOVA | p value | |||
N | 22 | 22 | ||||
Age | 20.3 (±5.2) | 19.7(±5.1) | 0.120 | 0.730 | ||
Gender (% of female) | 17 (77%) | 15 (68%) | 0.442 | 0.510 | ||
Full IQ (mean (SD)) Benton face recognition | 74 (±12) | 118 (±11) | 162.8 | < 0.01 | ||
39.4 (3.9) | 47.6 (2.9) | 60.1 | 0.001 | |||
SRS (mean (SD))* | SRS awareness | 58 (±12) | 47 (±9) | 7.4 | 0.001 | |
SRS cognition | 57 (±9) | 45 (±6) | 17.4 | < 0.001 | ||
SRS communication | 58 (±11) | 45 (±5) | 20.4 | < 0.001 | ||
SRS motivation | 60 (±12) | 44 (±6) | 18.1 | < 0.001 | ||
SRS RRB | 58 (±11) | 45 (±5) | 20.4 | < 0.001 | ||
SRS Total | 51 (±12) | 44 (±6) | 18.1 | < 0.001 | ||
Psychiatric diagnosis (N (%)) | Major depression disorder | 5 (23%) | ||||
Specific phobia | 3 (13%) | |||||
Simple phobia | 1 (4%) | |||||
Generalized anxiety disorder | 3 (13%) | |||||
Obsessive compulsive disorder | 1 (4%) | |||||
Alcohol dependence | 1 (4%) | |||||
Oppositional defiant disorder | 1 (4%) | |||||
Delusions | 2 (8%) | |||||
ADHD | 3 (13%) | |||||
Psychotropic medication | Categories | Antipsychotics | 1 (4%) | |||
Antidepressants | 7 (32%) | |||||
Methylphenidate | 4 (18%) |