Load matters: neural correlates of verbal working memory in children with autism spectrum disorder

Table 2 Linear trend analyses across difficulty levels for TD children

	Voxels	MNI coordinates			Z value	p value	Hem.	Region
	Voxels	x	y	z	Z value	p value	Hem.	Region
Regions where activation increases with difficulty (increasing BOLD signal)	14,922	− 28	− 76	− 4	4.81	6.31 × 10⁻²⁵	L	Middle occipital gyrus
	x	− 24	− 62	52	4.73		L	Superior parietal lobule
	x	− 26	− 72	− 10	4.51		L	Fusiform gyrus
	x	− 20	− 92	16	4.5		L	Cuneus
	x	28	− 58	58	4.44		R	Inferior parietal lobule
	14,033	− 8	18	42	5.41	6.92 × 10⁻²⁴	L	Cingulate gyrus
	x	− 40	2	30	4.96		L	Inferior frontal gyrus
	x	10	22	38	4.83		R	Cingulate gyrus
	x	− 4	28	28	4.76		L	Anterior cingulate cortex
	3447	50	32	32	4.57	9.29 × 10⁻⁹	R	Middle frontal gyrus
	x	32	18	3	4.47		R	Insula
Regions where activation decreases with difficulty (decreasing BOLD signal)	5355	2	38	− 22	5.38	4.32 × 10⁻¹²	R	Medial frontal gyrus
	x	− 6	40	− 12	4.74		L	Medial frontal gyrus
	x	− 14	34	− 16	4.51		L	Inferior frontal gyrus
	x	6	62	− 6	4.5		R	Superior frontal gyrus
	x	2	14	− 6	4.41		R	Anterior cingulate cortex
	5165	− 60	− 26	− 18	4.72	8.85 × 10⁻¹²	L	Middle temporal gyrus
	x	− 40	− 78	40	4.54		L	Precuneus/angular gyrus
	x	− 56	− 62	30	4.46		L	Angular gyrus
	4472	60	− 22	20	4.84	1.31 × 10⁻¹⁰	R	Supramarginal gyrus
	x	66	− 30	34	4.56		R	Inferior parietal lobule
	x	60	− 56	2	4.45		R	Middle temporal gyrus
	x	68	− 38	12	4.24		R	Superior temporal gyrus
	3615	− 16	− 48	36	4.25	4.5 × 10⁻⁹	L	Cingulate gyrus
	x	2	− 44	34	4.04		R	Cingulate gyrus

ISSN: 1866-1955