Fig. 7

Altered corticocollicular topography in the SC of Fmr1^−/y mice. a Schematic of tracing paradigm to assess retinocollicular topography. b, c Whole mount images of the SC (dashed area) reveal the termination zones (TZs) of focally labeled retinal ganglion cells in Fmr1^+/y (b) and Fmr1^−/y (c) mice. d Quantification of the TZ size as a percent of the SC. e Schematic of tracing paradigm to assess corticocollicular topography. f, g Parasagittal sections through the SCs (dashed area) of Fmr1^+/y (f) and Fmr1^−/y (g) mice reveal the TZ of Layer 5 neurons labeled in the visual cortex. h Quantification of the TZ size as a percent of the SC. For d and h, individual values for each identified neuron are shown, and the bar indicates the mean. *p < 0.05, Kolmogorov-Smirnov test