Fig. 2

Relationship between regional neonatal structural connectivity measures and developmental outcomes in preterm children. a Boxplots of hemispheric asymmetry between neonatal left and right inferior temporal lobe white matter fractional anisotropy in very preterm infants scanned at term-equivalent age and Bayley-III Motor Composite Categories based upon assessments performed at age 2 years, corrected. b Regression plot demonstrating the relationship between fractional anisotropy in the left cingulum bundle at term-equivalent age and competence scores on the Infant Toddler Social Emotional Assessment (ITSEA) tool at age 2 years, corrected. Note the association between more impaired (lower) ITSEA competence scores and higher FA (p = .001). Adapted with permission from Rogers CE, et al. Pediatric Research. 2016; 79(1-1):87–95