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Table 1 Participant characteristics

From: The reach-to-grasp movement in infants later diagnosed with autism spectrum disorder: a high-risk sibling cohort study

 

LR controls

HR-N

HR-ASD

Number

10

10

10

Age first visit (mos)

6.94 ± 1.82

7.06 ± 1.29

8.56 ± 2.14

Age diagnostic visit (mos)

36.84 ± 1.13

37.23 ± 1.8

37.66 ± 1.98

Sex

7 boys; 3 girls

3 boys; 7 girls*

6 boys; 4 girlso

AOSI total score

 6 months

11.11 ± 4.13

10.38 ± 3.58

14.75 ± 2.50

 9 months

6.89 ± 1.83

8.89 ± 3.55

7.22 ± 2.77

 12 months

5.00 ± 2.05

7.60 ± 3.41

9.70 ± 5.21*

 15 months

4.50 ± 3.72

8.40 ± 4.86

10.0 ± 5.16*

ADOS severity score

 18 months

7.70 ± 5.29

9.20 ± 5.40

14.80 ± 5.90*o

 24 months

5.50 ± 3.03

6.70 ± 4.90

14.90 ± 6.10*o

 36 months

4.20 ± 4.94

5.00 ± 3.50

17.30 ± 4.10*o

ADI–R total score

6.60 ± 2.76

9.10 ± 2.28

19.80 ± 10.80*o

MSEL ELC

123.60 ± 15.71

106.60 ± 11.31

96.44 ± 21.18*

VABS ABC

102.20 ± 7.21

89.88 ± 12.03

75.83 ± 11.94*

  1. Values reported are means + standard deviations. Significant difference from *LR control; oHR-N, ps < .0167. Note: reaches were scored at 6 and 9 months (where available) and at 12, 15, 18, 24, and 36 months
  2. LR low-risk, HR-N high-risk and not diagnosed with ASD, HR-ASD high-risk and diagnosed with ASD, N total sample, mos months, AOSI Autism Observation Scale for Infants, ADOS Autism Diagnostic Observation Schedule, ADI Autism Diagnostic Interview—Revised, MSEL ELC Mullen Scales of Early Learning Early Learning Composite ELC, VABS ABC Vineland Adaptive Behavior Scales Adaptive Behavior Composite ABC