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Fig. 3 | Journal of Neurodevelopmental Disorders

Fig. 3

From: Cognitive training for children and adolescents with fragile X syndrome: a randomized controlled trial of Cogmed

Fig. 3

Composite visual memory score (a; primary outcome; mean of Leiter Spatial Span and SB-5 Block Span) and b auditory working memory score (WISC IV Digit Span) at baseline, post-training, and at 3-month follow-up (no training), by Cogmed version (RM, higher functioning, N = 36; JM, lower functioning, N = 64) and by treatment condition (adaptive, N = 50 vs. non-adaptive control, N = 50) in children and adolescents with fragile X syndrome. Adaptive and non-adaptive groups combined demonstrated significant gains in visual and auditory working memory after training (p < .0001), and significant gains in auditory working memory also continued after 3 months of no treatment (p < .05). Post hoc analyses demonstrated significant improvement in the JM adaptive compared to non-adaptive groups from baseline to post-training (a), but no relative difference in efficacy for the RM version. Scores are raw observed scores ± SEM

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