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Table 1 Demographic information for participants with Cornelia de Lange and fragile X syndromes at T1, T2 and T3

From: Lifespan trajectory of affect in Cornelia de Lange syndrome: towards a neurobiological hypothesis

 

CdLS

FXS

t/U/χ2

p value

Time 1

 n

 

44

95

  

 Gender

% male

36.4

100.0

75.70

< 0.001

 Age (years)

Mean (SD) range

18.39 (10.04) 4.02–40.75

17.29 (9.14) 6.61–47.49

1952.00

ns

 T1 Self-help skills

% partly able/able

50.0

87.4

22.73

< 0.001

 T1 SCQa total score

Mean (SD)

20.14 (6.22)

20.19 (6.11)

.086

ns

 T2 Self-help skills

% partly able/able

45.9

87.7

29.86

< 0.001

 T2 SCQ total score

Mean (SD)

20.26 (6.08)

20.12 (6.64)

.240

ns

 T3 Self-help skills

% partly able/able

52.3

92.6

30.45

< 0.001

 T3 SCQ total score

Mean (SD)

17.30 (4.60)

18.44 (6.08)

−.930

ns

  1. n may vary due to missing data; ns = not significant
  2. aThe Autism Screening Questionnaire (ASQ [31]) was used at T1 and T2 as the SCQ was not available. The ASQ and SCQ differ on one item (item 20: social chat) and so for consistency this item was treated as missing data and was prorated for nonverbal participants (see [27])