Skip to main content

Table 3 Comparison between males and females on key ADOS-2 items

From: Intellectual functioning and behavioural features associated with mosaicism in fragile X syndrome

 

Males

Females

p

n

% atypical

n

% atypical

SA

 Pointing

62

71.0

17

76.5

0.767

 Gestures

83

55.4

32

37.5

0.099

 Eye contact

83

81.9

32

53.1

0.004*

 Facial expressions

83

88.0

32

71.9

0.050

 Shared enjoyment

83

49.4

32

18.8

0.003*

 Showing

62

77.4

17

35.3

0.002*

 Response to joint attention

62

29.0

17

11.8

0.212

 Initiation of joint attention

62

71.0

17

29.4

0.004*

 Quality of social overtures

83

88.0

32

75.0

0.095

 Rapport

83

72.3

32

46.9

0.016*

RRB

 Sensory

83

62.7

32

31.3

0.003*

 Mannerisms

83

59.0

32

46.9

0.296

 Repetitive and stereotyped behaviours

83

73.5

32

68.8

0.646

 Stereotyped language

62

78.7

27

63.0

0.187

Other

 Use of body as tool

39

38.5

9

11.1

0.238

 Response to name

62

43.5

17

11.8

0.022*

 Social smile

33

51.5

6

16.7

0.190

 Amount of social overtures (examiner)

83

72.3

32

37.5

0.001*

 Amount of social overtures (caregiver)

48

55.1

16

6.3

0.001*

 Amount of reciprocal communication

42

66.7

23

30.4

0.009*

 Functional play

62

69.4

17

29.4

0.005*

 Imaginative/creative play

83

94.0

31

67.7

0.001*

 Self-injury

83

12.0

32

0.0

0.060

 Anxiety

83

36.1

31

35.5

0.999

  1. All p values computed using Fisher’s exact test
  2. *p value remained < 0.05 after adjusting for multiple testing using FDR