Table 5 Comparison of females by allelic class on corrected intellectual functioning, ASD features and maladaptive behaviours
From: Intellectual functioning and behavioural features associated with mosaicism in fragile X syndrome
| Â | FM-only | PM/FM Mosaic | Â | ||
|---|---|---|---|---|---|
n | Mean ± SD | n | Mean ± SD | p | |
Intellectual functioning1 | |||||
 cVIQ | 28 | 70.7 ± 17.0 | 8 | 85.9 ± 20.0 | 0.024* |
 cPIQ | 28 | 66.2 ± 17.2 | 8 | 78.8 ± 12.3 | 0.006* |
 cWMI | 9 | 59.8 ± 17.2 | 4 | 80.0 ± 15.0 | 0.021* |
 cPSI | 16 | 75.3 ± 19.0 | 6 | 92.7 ± 18.1 | 0.014* |
 cFSIQ | 28 | 64.5 ± 17.3 | 8 | 79.4 ± 15.2 | 0.019* |
ASD features2 | |||||
 ADOS CSS | 24 | 4.75 ± 2.09 | 8 | 3.88 ± 2.85 | 0.806 |
 SA CSS | 24 | 4.71 ± 2.03 | 8 | 4.13 ± 2.59 | 0.664 |
 RRB CSS | 24 | 6.67 ± 2.30 | 8 | 4.63 ± 3.16 | 0.523 |
Maladaptive behaviours2 | |||||
 Irritability | 27 | 11.8 ± 12.0 | 7 | 3.57 ± 3.51 | 0.036* |
 Lethargy | 27 | 5.44 ± 5.73 | 7 | 1.43 ± 1.90 | 0.037* |
 Stereotypy | 27 | 3.48 ± 4.58 | 7 | 0.00 ± 0.00 | NA |
 Hyperactivity | 27 | 8.33 ± 7.69 | 7 | 0.86 ± 0.90 | < 0.001* |
 Inappropriate speech | 27 | 3.19 ± 3.04 | 7 | 0.29 ± 0.49 | 0.001* |
 Social avoidance | 27 | 2.67 ± 3.34 | 7 | 1.29 ± 2.56 | 0.429 |
 ABC Total | 27 | 34.9 ± 30.3 | 7 | 7.43 ± 6.40 | 0.001* |
 ABC UI | 27 | 0.69 ± 0.21 | 7 | 0.88 ± 0.06 | 0.005* |