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Fig. 1 | Journal of Neurodevelopmental Disorders

Fig. 1

From: Refining the concept of GFAP toxicity in Alexander disease

Fig. 1

Increase in activity of the Gfap promoter during early postnatal development of a mouse model of Alexander disease. Promoter activity (monitored through expression of a Gfap-luciferase reporter) in mutants rises above that in wild-type mice between postnatal days 7 to 14 and remains elevated through at least 8 weeks of age. Figure used with permission [11]

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