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Fig. 5 | Journal of Neurodevelopmental Disorders

Fig. 5

From: Guanfacine treatment improves ADHD phenotypes of impulsivity and hyperactivity in a neurofibromatosis type 1 mouse model

Fig. 5

Guanfacine (GUAN, 0.3 mg/kg) attenuates deficits in behavioral inhibition in Nf1+/− mice in the cliff avoidance reaction (CAR) test. Graphs illustrate the effects of Nf1+/− on the a total distance traveled (m), b % mice with impaired CAR, and c stereotypy rating scores. *p < 0.05 compared to wild-type (WT) within the same treatment. #p < 0.05 compared to vehicle (VEH) within the same genotype. All data reported as mean + S.E.M

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Journal of Neurodevelopmental Disorders

ISSN: 1866-1955

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