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Table 8 Group comparison for distributions of allele categories and % methylation for mosaic alleles between patients on lovastatin vs. placebo

From: Controlled trial of lovastatin combined with an open-label treatment of a parent-implemented language intervention in youth with fragile X syndrome

Variable

Lovastatin+PILI

Placebo+PILI

Between-group comparison

Allele category,n (%)

  

Fisher’s exact test Prob = 0.0211 (0.1717)

 Full mutation

9 (75%)

7 (43.75%)

 Methylation mosaic

0

4 (25%)

Size mosaic

3 (25%)

5 (31.25%)

% Methylation for mosaic alleles, mean ± SD

85.67 ± 9.29

75.22 ± 11.98

F(1, 10) = 1.86 (0.2026)