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Table 8 Group comparison for distributions of allele categories and % methylation for mosaic alleles between patients on lovastatin vs. placebo

From: Controlled trial of lovastatin combined with an open-label treatment of a parent-implemented language intervention in youth with fragile X syndrome

VariableLovastatin+PILIPlacebo+PILIBetween-group comparison
Allele category,n (%)  Fisher’s exact test Prob = 0.0211 (0.1717)
 Full mutation9 (75%)7 (43.75%)
 Methylation mosaic04 (25%)
Size mosaic3 (25%)5 (31.25%)
% Methylation for mosaic alleles, mean ± SD85.67 ± 9.2975.22 ± 11.98F(1, 10) = 1.86 (0.2026)