Fig. 4From: Firing activity of locus coeruleus noradrenergic neurons decreases in necdin-deficient mice, an animal model of Prader–Willi syndromeDevelopmental reflexes and body weight of wild-type (WT) and Ndn +m/−p mice. a–c Transient hypotonia was observed in Ndn +m/−p mice (n = 10 animals) than WT (n = 8 animals) by increased latencies of surface righting (a) and negative geotaxis reflexes (c) and decreased latencies of bar holding (b) at postnatal day (P) 5. d WT (n = 13 animals) and Ndn +m/−p mice (n = 14 animals) showed equivalent body weight gain from postnatal days 3 to 21. Statistical analyses were performed using Student’s t test. Data are presented as mean ± SEMBack to article page