Fig. 3

PCA plots of NDD-associated CpGs and relative PC1 scores in controls, “less symptomatic”, and “more symptomatic” individuals with ADHD and OCD. a Samples sizes and number of CpGs input into PCA shown in bottom, right-hand corner of each facet. b PC1 scores of PCA run on 299 CpGs differentially methylated between controls and the more symptomatic ADHD subset, with “less symptomatic” samples included in PCA (n controls = 27, n ADHD less symptomatic = 7, n ADHD more symptomatic = 15). c PC1 scores of PCA run on 137 CpGs differentially methylated between controls and the more symptomatic OCD subset with “less symptomatic” samples included in PCA (n controls = 54, n OCD less symptomatic = 11, n OCD more symptomatic = 28, n = 20 removed due to missing CY-BOCS scores). Comparisons were performed using ANOVA and marked by asterisks if significant (Tukey p values < 0.05)