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Fig. 5 | Journal of Neurodevelopmental Disorders

Fig. 5

From: Protective role of mirtazapine in adult female Mecp2+/− mice and patients with Rett syndrome

Fig. 5

Effects of long MTZ treatment on MBAS subitems and sleep disturbances in RTT patients. a Irritability and aggressiveness, b social interactions, c motor dysfunctions, d respiratory and autonomic dysfunctions, and e night awakenings. (Complete results are shown in Table 4). All data are expressed as boxplots. In all cases, according to results of Shapiro-Wilk test, we used paired Student’s t test or Mann-Whitney test to compare averages between treated (n = 11) and untreated (n = 11) groups. ns: p > 0.05 (not shown); *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001

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