Fig. 5
From: Deficits in higher visual area representations in a mouse model of Angelman syndrome
Stimulus-evoked inhibitory activity modulation is reduced in AS mice. a Diagram of how activity modulation in response to “speed up” (SU) was calculated. The difference in average activity before and after the 10➔50°/s transition was calculated for each cell responsive to the stimulus. b, c Population responses of V1 (b) and AL (c) inhibitory neurons in response to the SU component. Insets show average activity modulation across the cell population. d Summary of average inhibitory activity modulation to SU by region and genotype. e Diagram of how activity modulation in response to “slow down” (SD) component was calculated. The difference in average activity before and after the 50➔10°/s transition was calculated for each cell response to the stimulus. f, g Population responses of V1 (f) and AL (g) inhibitory neurons in response to the SD component. Insets show average activity modulation across the cell population. h Summary of average inhibitory activity modulation to SD by region and genotype. Two-tailed t test. ***p < 0.001; ****p < 0.0001