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Fig. 1 | Journal of Neurodevelopmental Disorders

Fig. 1

From: Translational outcomes relevant to neurodevelopmental disorders following early life exposure of rats to chlorpyrifos

Fig. 1

Early life CPF exposure reduces USV emission in male and female rat pups in a dose- and time-dependent manner. a Male pups exposed to 1.0 mg/kg/day CPF emitted fewer USV compared to vehicle controls on PND 12. By PND 16, all three male CPF exposure groups had significantly lower USV emission than controls. b In females, exposure to 0.3 mg/kg/day CPF led to reduced pup USV emission on PND 12 and 16. c, d Body temperature and e, f body weight immediately following USV collection were similar across exposure groups, eliminating these two variables as potential confounds on call quantity. Data are mean ± S.E.M. *p < 0.05, repeated measures ANOVA, Holm-Sidak’s multiple comparisons test post hoc

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