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Table 3 Adjusted multivariable logistic regression models estimating odds of diagnosis (ASD with ID, ASD without ID, ID only) given each air pollutant (NO2, ozone, PM10, PM2.5) for a 1 Unit change in exposure

From: Maternal immune response and air pollution exposure during pregnancy: insights from the Early Markers for Autism (EMA) study

Predictors

Outcome: ASD with ID (vs GP)

Outcome: ASD without ID (vs GP)

Outcome: ID only (vs GP)

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

NO2

0.99

(0.97, 1.01)

0.31

1.00

(0.98, 1.02)

0.83

0.99

(0.96, 1.01)

0.34

Child sex (male)

0.88

(0.55, 1.39)

0.58

0.89

(0.56, 1.41)

0.62

0.30

(0.19, 0.45)

< 0.01

Year of birth

0.96

(0.78, 1.18)

0.71

1.04

(0.85, 1.27)

0.69

0.82

(0.65, 1.03)

0.09

Month of birth

1.01

(0.95, 1.08)

0.69

0.98

(0.92, 1.04)

0.56

0.99

(0.92, 1.05)

0.68

SD County (vs Imperial/Orange)

1.82

(1.26, 2.61)

< 0.01

1.63

(1.14, 2.32)

0.01

2.23

(1.49, 3.33)

< 0.01

Public insurance

0.87

(0.60, 1.27)

0.47

0.46

(0.30, 0.69)

< 0.01

2.59

(1.75, 3.83)

< 0.01

 

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

Ozone

1.01

(0.99, 1.02)

0.50

1.00

(0.98, 1.02)

0.95

1.00

(0.98, 1.02)

0.87

Child sex (male)

0.88

(0.55, 1.39)

0.57

0.89

(0.56, 1.41)

0.62

0.29

(0.19, 0.45)

< 0.01

Year of birth

0.97

(0.79, 1.19)

0.76

1.05

(0.86, 1.27)

0.66

0.85

(0.68, 1.06)

0.15

Month of birth

1.02

(0.96, 1.08)

0.52

0.98

(0.93, 1.04)

0.59

1.00

(0.94, 1.07)

0.99

SD County (vs Imperial/Orange)

1.85

(1.29, 2.65)

< 0.01

1.64

(1.16, 2.32)

0.01

2.31

(1.55, 3.44)

< 0.01

Public insurance

0.86

(0.59, 1.26)

0.45

0.46

(0.30, 0.69)

< 0.01

2.57

(1.74, 3.80)

< 0.01

 

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

PM10

0.99

(0.97, 1.01)

0.45

0.99

(0.97, 1.01)

0.34

1.02

(1.00, 1.04)

0.07

Child sex (male)

0.86

(0.55, 1.37)

0.53

0.89

(0.56, 1.41)

0.63

0.29

(0.19, 0.45)

< 0.01

Year of birth

0.97

(0.79, 1.19)

0.77

1.03

(0.85, 1.25)

0.77

0.88

(0.70, 1.09)

0.24

Month of birth

1.02

(0.96, 1.08)

0.59

0.98

(0.92, 1.04)

0.42

1.02

(0.95, 1.09)

0.59

SD County (vs Imperial/Orange)

1.72

(1.13, 2.62)

0.01

1.49

(1.00, 2.22)

0.05

2.86

(1.79, 4.55)

< 0.01

Public insurance

0.87

(0.59, 1.26)

0.46

0.46

(0.30, 0.69)

< 0.01

2.54

(1.72, 3.76)

< 0.01

 

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

PM2.5

0.97

(0.93, 1.00)

0.06

1.00

(0.96, 1.03)

0.89

0.98

(0.95, 1.02)

0.41

Child sex (male)

0.89

(0.56, 1.41)

0.61

0.89

(0.56, 1.41)

0.62

0.29

(0.19, 0.45)

< 0.01

Year of birth

0.96

(0.78, 1.17)

0.66

1.04

(0.86, 1.27)

0.66

0.83

(0.67, 1.04)

0.10

Month of birth

1.00

(0.94, 1.07)

0.91

0.98

(0.92, 1.05)

0.58

0.99

(0.92, 1.06)

0.73

SD County (vs Imperial/Orange)

1.61

(1.09, 2.38)

0.02

1.62

(1.12, 2.37)

0.01

2.15

(1.41, 3.29)

< 0.01

Public insurance

0.87

(0.6, 1.27)

0.48

0.46

(0.30, 0.69)

< 0.01

2.57

(1.74, 3.80)

< 0.01

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Journal of Neurodevelopmental Disorders

ISSN: 1866-1955

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