Table 1 List of epigenetic modifiers that are mutated in children with developmental disorders but have also been described as mediators of the hypoxic response
Overlap between genetic developmental disorders and hypoxic response | ||
|---|---|---|
DNA methylation | Histone modifications | |
DNMT3A | CHD7 | HDAC4 |
DNMT3B | CHD8 | KMT2D |
MeCP2 | p300 | KDM6A |