Fig. 3From: Controlling litter effects to enhance rigor and reproducibility with rodent models of neurodevelopmental disordersa When litter effect is ignored, the variation in body, brain, and placental weights of wild-type (WT) and Chd8V986*/+ mutant mice at E15.5 varies greatly. b Adjusting for the litter effect removes unexplained variation in the data and has the potential to unmask significant differences between groupsBack to article page