Table 1 Litters are rarely used as the statistical unit in NDD publications
Category | Search criteria | Number of litters indicated | Litter treated as statistical unit |
|---|---|---|---|
Genetic (including molecular studies of brain development) | (SCN2A AND Autism) OR (CHD8 AND Autism) OR (UBE3A AND Angelman) | 2/45 (4%) | 0/45 (0%) |
neocortex AND development AND regulation | 3/29 (10%) | 1/29 (3%) | |
(embryonic knockout OR electroporation) AND brain development | 4/25 (16%) | 1/25 (4%) | |
Genetic total | Â | 9/99 (9%) | 2/99 (2%) |
Environment | maternal immune activation AND autism | 23/33 (67%) | 6/33 (18%) |
autism AND air pollution | 8/9 (89%) | 3/9 (33%) | |
BPA AND brain development | 8/9 (89%) | 4/9 (44%) | |
autism AND VPA | 30/66 (45%) | 10/66 (15%) | |
Environment total | Â | 69/117 (59%) | 23/117 (20%) |