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Table 2 Behavioral and clinical measures of interest

From: Quantitative trait variation in ASD probands and toddler sibling outcomes at 24 months

Domain(s)

Probands

Siblings

Parent interview

Parent interview

Examiner-based

Autism traits

ADI-R, SCQ

ADI-R

ADOS

General ability/adaptive behavior

VABS-II: ABC, SOC

VABS-II: ABC, SOC

MSEL: ELC

Communication/language

VABS-II: COM, EL, RL

VABS-II: COM, EL, RL

MSEL: EL, RL

Motor

VABS-II: MS, GM, FM

VABS-II: MS, GM, FM

MSEL: GM, FM

  1. ADI-R Assessments include the Autism Diagnostic Interview-Revised, ADOS Autism Diagnostic Observation Schedule, SCQ Social Communication Questionnaire, VABS-II Vineland Adaptive Behavior Scales Second Edition, and the MSEL Mullen Scales of Early Learning
  2. Measures of interest from the MSEL and VABS-II include ABC adaptive behavior composite, ELC Early Learning Composite, SOC socialization, COM communication, EL, RL expressive and receptive language, MS motor skills, GM, FM gross and fine motor
  3. Higher scores on the ADI-R, SCQ, and ADOS indicate greater endorsement of ASD symptoms: higher scores on the VABS-II and MSEL indicate better adaptive and cognitive skills