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Table 4 Linear regression analyses: VABS-II parent-reported behavior

From: Quantitative trait variation in ASD probands and toddler sibling outcomes at 24 months

 Betaa95% CI lower95% CI upperp value
ABC model (n = 303)
 Proband ABC0.330.110.550.004+
 Sibling sex− 0.27− 0.48− 0.070.009
 Group0.990.751.23< 0.0001
 Proband score x group− 0.18− 0.430.070.149
SOC model (n = 311)
 Proband SOC0.250.040.460.022
 Sibling sex− 0.33− 0.53− 0.140.001
 Group0.880.641.12< 0.0001
 Proband score x group− 0.21− 0.450.030.089
COM model (n = 309)
 Proband COM0.400.200.61< 0.0001+
 Sibling sex− 0.16− 0.350.040.113
 Group1.070.831.30< 0.0001
 Proband score x group− 0.28− 0.51− 0.040.021
EL model (n = 317)
 Proband EL0.440.230.65< 0.0001+
 Sibling sex− 0.23− 0.44− 0.030.028
 Group0.800.551.04< 0.0001
 Proband score x group− 0.36− 0.60− 0.120.003+
RL model (n = 318)
 Proband RL0.530.320.73< 0.0001+
 Sibling sex− 0.08− 0.270.120.429
 Group1.050.821.28< 0.0001
 Proband score x group− 0.42− 0.65− 0.19< 0.0001+
GM model (n = 277)
 Proband GM0.22− 0.050.500.113
 Sibling sex0.03− 0.220.270.832
 Group0.550.270.84< 0.0001
 Proband score x group− 0.01− 0.320.290.933
  1. ABC Adaptive Behavior Composite, SOC socialization composite, COM communication composite, EL expressive language, RL receptive language, GM gross motor
  2. aStandardized beta coefficients from linear regression models. Reference groups for sibling sex and group are female (vs. male) and ASD (vs. no ASD), respectively. Full model results are shown in Additional file 1: Table S4
  3. +significant at p ≤ 0.004 after Bonferroni correction for main and interacting effects of proband score (12 comparisons)