TY - JOUR AU - Black, Conner J. AU - Hogan, Abigail L. AU - Smith, Kayla D. AU - Roberts, Jane E. PY - 2021 DA - 2021/03/20 TI - Early behavioral and physiological markers of social anxiety in infants with fragile X syndrome JO - Journal of Neurodevelopmental Disorders SP - 11 VL - 13 IS - 1 AB - Social anxiety is highly prevalent in neurotypical children and children with fragile X syndrome (FXS). FXS is a genetic syndrome that is characterized by intellectual disability and an increased risk for autism spectrum disorder. If social anxiety is left untreated, negative outcomes are highly prevalent later in life. However, early detection of social anxiety is challenging as symptoms are often subtle or absent very early in life. Given the prevalence and impairment associated with childhood social anxiety, efforts have accelerated to identify risk markers of anxiety. A cluster of early features of anxiety have been identified including elevated behavioral inhibition, attentional biases, and physiological dysregulation that index early emerging markers of social anxiety. Infants with FXS provide a unique opportunity to study the earlier predictors of social anxiety. The current study utilized a multi-method approach to investigate early markers of social anxiety in 12-month-old infants with FXS. SN - 1866-1955 UR - https://doi.org/10.1186/s11689-021-09356-3 DO - 10.1186/s11689-021-09356-3 ID - Black2021 ER -