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Table 1 Summary of clinical measures

From: Modeling familial predictors of proband outcomes in neurogenetic disorders: initial application in XYY syndrome

 

Probands

(N = 58)

Siblings

(N = 24)

Mothers

(N = 57)

Fathers

(N = 34)

Mean + standard deviation (range)

Visit age (years)

12.6 + 5.39

(5.4–25.9)

13.4 + 6.1

(5.5–26.9)

44.8 + 7.0

(31.7–61.3)

44.0 + 5.5

(34.9–57.3)

FSIQ

N = 57/24/56/32

86.65 + 13.96

(53–112)

104.17 + 14.24

(70–128)

106.3 + 9.27

(90–133)

109.0 + 11.76

(84–135)

Vocabulary

N = 45/23/56/32

7.11 + 2.91

(1–14)

10.52 + 2.33

(5–15)

10.82 + 2.10

(8–17)

11.5 + 2.14

(8–16)

Matrix reasoning

N = 58/24/57/34

8.97 + 3.05

(2–16)

11.29 + 3.44

(1–18)

11.53 + 1.99

(6–15)

11.82 + 2.69

(5–18)

SRS-2 Total

N = 58/24/57/34

66.4 + 13.18

(42–100)

45.25 + 6.42

(37–66)

49.09 + 6.46

(39–66)

52.53 + 7.37

(40–76)

SRS-2 Awareness

66.67 + 13.21

(45–104)

48.62 + 10.37

(32–69)

52.37 + 5.91

(38–66)

55.91 + 7.1

(44–78)

SRS-2 Cognition

65.64 + 12.72

(44–100)

46.38 + 7.44

(39–70)

48.19 + 7.96

(37–65)

50.0 + 6.56

(39–70)

SRS-2 Communication

66.34 + 13.46

(40–96)

45.08 + 6.14

(38–64)

48.75 + 7.18

(38–75)

53.0 + 8.31

(41–78)

SRS-2 Motivation

60.33 + 12.05

(42–93)

46.46 + 7.56

(37–66)

51.68 + 9.12

(37–71)

54.62 + 10.01

(37–76)

SRS-2 RIRB

63.9 + 14.03

(41–100)

44.25 + 4.38

(40–58)

47.02 + 6.08

(40–70)

49.68 + 7.38

(40–72)

SRS-2 SCI

66.6 + 12.75

(43–99)

45.75 + 7.08

(36–68)

49.81 + 6.68

(39–68)

53.47 + 7.6

(40–77)

ADHD inattentive

N = 55/23/57/34

73.15 + 12.61

(46–90)

55.78 + 11.42

(40–87)

48.26 + 15.32

(33–90)

48.06 + 14.35

(28–90)

ADHD hyperactive-impulsive

65.08 + 15.47

(40–90)

53.96 + 13.60

(35–86)

41.51 + 10.06

(29–79)

43.41 + 7.62

(32–62)

  1. FSIQ is reported as a standard score. Vocabulary and matrix reasoning are reported as scaled scores. All other measures are reported as T-scores. N shows the number of participant values (proband/sibling/mother/father) for each measure. The SRS-2 subscales have the same N as the SRS-2 Total Score. The ADHD measures have the same N for both ADHD-traits. FSIQ Full Scale Intelligence Quotient, SRS-2 Social Responsiveness Scale Second Edition. SRS-2 Awareness SRS-2 Social Awareness, SRS-2 Cognition SRS-2 Social Cognition. SRS-2 Communication SRS-2 Social Communication, SRS-2 Motivation SRS-2 Social Motivation, SRS-2 RIRB SRS-2 Restricted Interests and Repetitive Behaviors, SRS-2 SCI SRS-2 DSM-5 Social Communication and Interaction