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Table 2 Description of primary measures

From: Capturing cognitive and behavioral variability among individuals with Down syndrome: a latent profile analysis

Domain of assessment

Measure

Outcome variablea

Interpretation of score

Performance-based assessments of cognition

 Verbal + nonverbal intelligence

KBIT-2

Raw score composite

Higher score = more skills

 Working memory (immediate memory for spatial-temporal sequences)

CANTAB Spatial Span

Forward span length

Higher score = more skills

 Visuomotor scanning and hand-eye coordination

NEPSY-II Visuomotor Precision, ages 3–4

Total score (time and number of errors)

Higher score = more skills

Caregiver-informed assessments of cognition and behavior

 Executive functioning

BRIEF School Age

Global Executive Composite standard score

Higher score = more impairments

 Adaptive

SIB-R Short Form

Standard score composite

Higher score = more adaptive skills

 Maladaptive

NCBRF

Conduct problems, insecure/anxious, and hyperactivity subscale raw scores

Higher score = more maladaptive behaviors

 Autism spectrum disorder (ASD) symptomatology

SCQ-Lifetime

Total raw score

Higher score = more ASD-like symptoms

  1. KBIT-2 Kaufman Brief Intelligence Test, 2nd edition, CANTAB Cambridge Neuropsychological Test Automated Battery, BRIEF Behavioral Rating Inventory of Executive Function, SIB-R Scales of Independent Behavior-Revised, NCBRF Nisonger Child Behavior Rating Form, SCQ Social Communication Questionnaire
  2. aAll outcome variables were age-corrected