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Fig. 2 | Journal of Neurodevelopmental Disorders

Fig. 2

From: Reflections on the genetics-first approach to advancements in molecular genetic and neurobiological research on neurodevelopmental disorders

Fig. 2

Distribution of dnLGD and dnMIS for 17 top NDD risk genes. DNVs were collected from unique samples of 10,927 NDD (5624 ASD and 5303 DD/ID) trios in denovo-db v1.5 [60], 465 ASD trios from the SPARK pilot study [62], and 3625 ASD trios from ASC study [54]. Samples that overlapped across studies were only counted once. The number of dnLGD and dnMIS is listed next to each gene, and the relative positioning of each variant was scaled in 1 to 100% based on the size of each gene

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