Fig. 3

Effects of JZL-184 treatment on resting EEG baseline in Fmr1 KO mice. Graphs show average spectral power for EEG resting baseline in left/right frontal, medial, and temporal regions of Fmr1 KO mice treated with 8 mg/kg JZL-184 (N = 13) 4 h and 1 day (N = 8) post-treatment as a ratio of Fmr1 KO mice prior to treatment (PRE, N = 22). Statistical analysis was performed using the two-way ANOVA for all comparisons. Values represent means per group and error bars represent the standard error of the mean (SEM). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Abbreviations: D, delta; T, theta; A, alpha; B, beta; LG, low gamma; HG, high gamma