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Table 1 Demographic and developmental characteristics of the cohort. Statistic pertains to comparison of variable versus quantitative IQ (not ID group). We used Wilcoxon rank-sum test to examine IQ across sex; Spearman rank correlation to correlate IQ with age and VABS-II scores; and logistic regression model to compare ASD diagnosis with IQ.

From: Parent-reported measure of repetitive behavior in Phelan-McDermid syndrome

  Mild ID Moderate ID Severe profound ID Entire cohort Statistic p-value
  Mean SD N Mean SD N Mean SD N Mean SD N   
Gender (% Female) 0.62   8 0.55   20 0.42   62 0.47   90 W = 1194 0.13
Age at evaluation (years) 7.48 1.32 8 11.69 5.03 20 8.15 4.58 62 8.88 4.72 90 rs = -0.08 0.45
VABS-II Adaptive Behavior Composite Standard Score 74.12 7.94 8 60.5 10.06 20 44.56 9.43 62 50.73 13.59 90 rs = 0.84 <0.0001
VABS-II Communication Standard Score 78 8.12 8 61.15 11.65 20 42.37 9 62 49.71 15.12 90 rs = 0.84 <0.0001
VABS-II Socialization Standard Score 82.38 12.59 8 64.6 12.43 20 50.47 10.71 62 56.44 14.98 90 rs = 0.76 <0.0001
VABS-II Daily Living Skills Standard Score 65.88 16.62 8 61.05 12.22 20 45.32 10.88 62 50.64 14.13 90 rs = 0.75 <0.0001
VABS-II Motor Standard Score 71.29 10.03 7 69.15 10.54 13 53.1 7.9 50 57.9 11.45 70 rs = 0.75 <0.0001
ASD (%) 0.14   7 0.35   20 0.73   59 0.59   86 IQ coefficient: estimate = -0.07, std error = 0.02 <0.0001