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Table 1 Demographics characteristics and clinical measures

From: Social communication in fragile X syndrome: pilot examination of the Brief Observation of Social Communication Change (BOSCC)

 

Visit 1

Overall (N = 18)

Visit 3

Overall (N = 7)

Age at consent (years)

 Mean (SD)

4.5 (1.54)

5.3 (1.60)

Sex

 Male, n (%)

18 (100.0%)

7 (100%)

Race

 African American or Black, n (%)

1 (5.6%)

0

 Caucasian or White, n (%)

12 (66.7%)

7 (100%)

 More than one race, n (%)

5 (27.8%)

0

Ethnicity

 Hispanic/Latino, n (%)

1 (5.6%)

0

 Not Hispanic or Latino, n (%)

17 (94.4%)

7 (100%)

Stanford Binet abbreviated IQ

57.6 (15.8, range = 47–103)

63.6 (20.35, range = 47–103)

 Verbal scaled score

2.6 (2.23, range = 1–8)

3.1 (2.12, range = 1–6)

 Nonverbal scaled score

2.5 (1.95, range = 1–6)

3.0 (2.24) (range = 1–6)

Current school year

 Pre-School, n (%)

12 (66.7%)

3 (42.9%)

 Kindergarten, n (%)

2 (11.1%)

2 (28.6%)

 Grade 1 to 12, n (%)

4 (22.2%)

2 (28.6%)

Primary caregiver highest education

 High school and below, n (%)

3 (16.7%)

3 (42.9%)

 College and above, n (%)

15 (83.4)

4 (57.1%)

Secondary caregiver highest education

 High school and below, n (%)

3 (16.7%)

1 (14.3%)

 College and above, n (%)

13 (82.3%)

6 (85.7%)

Social Responsiveness Scale-2 (raw scores)

 Awareness

17.2 (2.26)

18.4 (3.15)

 Cognition

29.1 (4.03)

30.3 (2.50)

 Communication

49.5 (4.71)

45.7 (4.57)

 Motivation

24.7 (3.82)

23.6 (4.79)

 Restrictive and repetitive behaviors

31.4 (4.08)

29.4 (3.10)

 Total

151.9 (12.82)

147.4 (12.41)

Aberrant Behavior Checklist

 Irritability

21.2 (11.61)

25.6 (14.13)

 Social unresponsiveness/lethargy

6.4 (4.19)

4.0 (3.96)

 Hyperactivity

15.9 (7.47)

16.0 (7.46)

 Inappropriate Speech

3.0 (2.70)

3.7 (2.87)

 Social Avoidance

2.4 (2.94)

2.1 (3.39)

 Stereotypic Behavior

7.7 (4.50)

5.9 (3.67)

Vineland-3 (raw scores)

  

 Expressive communication

32.5 (18.29)

61.4 (24.34)

 Receptive communication

43.4 (15.04)

56.9 (14.16)

  1. Abbreviations: n = number of subjects, SD = standard deviation. Percentages are calculated as n/N*100