Social behavior in RASopathies and idiopathic autism

Table 3 Psychiatric and neurodevelopmental diagnosis prevalence estimates in the literature as compared to this study cohort (%)

	NF1 (n = 71)	NS (n = 73)	CFCS (n = 40)	CS (n = 18)	iASD (n = 109)
ASD
Estimates	11–26 [16, 30, 38, 53]	0–30 [7, 14]	9–54 [6, 7]	11–26 [6, 7]	100
Our study	16	10	23	6	100
ADHD
Estimates	39 [72]	34–48 [10, 14]	47–89 [14, 73]	38 [7]	28–76 [74, 75]
Our study	41	25	15	6	47
Anxiety
Estimates	18–21 [72, 76]	7–8 [72, 77]	6 [73]	20–50 [12]^*	32–79 [78, 79]
Our study	18	14	28	22	37
Depression
Estimates	–	–	12 [73]	–	1–56 [74, 75]
Our study	11	6	0	0	13
Intellectual disability
Estimates	4–8 [80, 81]	6–23 [10, 82]	90–100 [5, 83, 84]	78–100 [5, 12, 29]	33 [20]
Our study	10	15	63	67	11

ISSN: 1866-1955