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Table 4 Social and behavioral ratings of children with RASopathies or idiopathic ASD

From: Social behavior in RASopathies and idiopathic autism

 

RASopathy

Idiopathic ASD

 

Measure

n

Mean

(SD)

% Clinical impairment (≥ 2 SD below mean)

n

Mean

(SD)

% Clinical impairment (≥ 2 SD below mean)

Mean difference (95% CI)

Social Emotional Assets & Resilience Scales (SEARS)

Social competence

149

39.57

(11.10)

19

87

30.49

(7.64)

48

9.08

6.43 to 11.73

Empathy

149

45.30

(11.16)

8

88

32.99

(9.39)

40

12.31

9.52 to 15.10

 

n

Mean

(SD)

% Clinical impairment (≥ 2 SD above mean)

n

Mean

(SD)

% Clinical impairment (≥ 2 SD above mean)

Mean difference (95% CI)

Strengths & Difficulties Questionnaire (SDQ)

Emotional symptoms

180

1.23

(1.45)

29

97

1.32

(1.29)

29

− 0.09

− .44 to .26

Conduct problems

180

0.48

(1.15)

11

97

0.71

(1.10)

17

− 0.23

− .51 to .06

Hyperactivity/inattention

180

1.33

(1.15)

32

97

1.59

(1.03)

46

− 0.26

− .54 to .01

Peer relationship problems

180

1.33

(1.42)

38

97

2.21

(1.11)

58

− 0.87

− 1.2 to − .55

Lack of prosocial behavior

180

0.83

(1.25)

22

97

1.79

(1.24)

44

− 0.96

− 1.27 to − .65

  1. SEARS scores are reported in T-scores with a mean of 50 and a standard deviation of 10. Higher SEARS scores indicate fewer problems; SDQ scores are reported in z-scores with a mean of 0 and a standard deviation of 1. Higher SDQ scores indicate more problems