The effect of autistic traits on response to and side-effects of pharmacological ADHD treatment in children with ADHD: results from a prospective clinical cohort

Table 4 Adverse events

Subcategory Organ system^b	Study Group				Chi-square test with continuity correction (P)
	Non-ASD (N = 257)^a		ASD (N = 66)^a
	No significant symptoms (n)	Significant symptoms (n)	No significant symptoms (n)	Significant symptoms (n)
Gastrointestinal	138	119	40	26	.385
Central nervous system	130	127	33	33	1.0
Endocrine	196	61	48	18	.663
Mood/behavior changes	225	32	52	14	.105
Cardiovascular	247	10	61	5	.347*
Immune system	253	4	65	1	1.0*
Skin	243	14	63	3	1.0*
Renal	250	7	64	2	1.0*
Sexual	256	1	66	0	1.0*
Other	252	5	64	2	.947*
Allergic	219	38	55	11	.851

Table displaying number of reported significant symptoms and No significant symptoms, for the Non-ASD symptoms group and the ASD symptoms group, subdivided in 11 organ systems
*The chi-squared approximation may be incorrect due to insufficient number
^aThe different number of individuals in the groups are due to multiple imputation. Using pooled values defining the groups, results in non-integer numbers. The chi-square tests are analyzed from pooled values
^bThe total range of score on the P-SEC scale is 0 to 196. However, in our analyses, the range was 0–49, after changing the items into dichotomous variables

ISSN: 1866-1955