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Table 1 Demographic and health related information across SAS developmental sub-groups and associated comparative analyses

From: The behavioural phenotype of SATB2-associated syndrome: a within-group and cross-syndrome analysis

 

Developmental sub-group

Comparative analysis

Pre-school

(PS; n = 30)

School-age

(SA; n = 35)

Adolescents & adults

(AA; n = 16)

Statistica

p value

Post hoc test

Demographics

 M age; years (SD)

4.27 (1.30)

9.67 (2.78)

24.19 (6.14)

186.018

< .001

PS < SA < AA

 Gender; n (% male)

15 (50.0)

16 (45.7)

12 (75.0)

3.964

.141

 

 Median self-help scoreb, c (IQR)

5.00 (4.00–7.00)

6.00 (5.00–7.00)

6.50 (5.25–7.75)

8.732

.013

 

 Mobilityd; n (% fully mobile)

25 (83.3)

35 (100.0)

15 (93.8)

-

.033

 

 Visionc; n (% normal)

23 (76.7)

31 (88.6)

13 (81.3)

-

.475

 

 Hearingc; n (% normal)

27 (90.0)

35 (100.0)

15 (93.8)

-

.141

 

 Speechd; n (% verbal)

6 (20.0)

13 (37.1)

7 (43.8)

3.420

.181

 

Health characteristics

 M GDQ clinical signs (SD)

6.10 (3.08)

4.80 (2.78)

5.19 (3.45)

1.517

.226

 

 Eye problemse; n (% present)

5 (16.7)

7 (20.0)

0 (0.0)

-

.161

 

 Ear problemse; n (% present)

6 (20.0)

4 (11.4)

3 (18.8)

-

.670

 

 Dental problemse; n (% present)

11 (36.7)

20 (57.1)

7 (43.8)

2.800

.247

 

 Cleft palatee; n (% present)

4 (13.3)

1 (2.9)

1 (6.3)

-

.240

 

 GI problemse; n (% present)

8 (26.7)

2 (5.7)

2 (12.5)

-

.062

 

 Epilepsye; n (% present)

6 (20.0)

7 (20.0)

0 (0.0)

-

.121

 

 Respiratory problemse; n (% present)

7 (23.3)

4 (11.4)

1 (6.3)

-

.326

 

 Skin problemse; n (% present)

7 (23.3)

11 (31.4)

4 (25.0)

-

.806

 
  1. Significant group differences highlighted in bold. Group difference italicised = test statistic approached statistical significance at p = .01 (deemed to approach statistical significance if p = .011 to .014). aTest statistic for multiple-group comparison; Chi-square, ANOVA, or Kruskal–Wallis tests performed. Where test statistic is not reported, there were less than five expected values in cells, and Fisher’s exact test was performed. bNoncategorical self-help scores were not normally distributed; therefore, Kruskal–Wallis test was conducted (median and IQR values reported). cData derived from Wessex Behavior Scale. dData derived from Background Information Questionnaire. eData derived from Health Questionnaire Part B; presence of health problem in the previous month (mild, moderate, and severe scores rated as present)