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Table 6 Item-level analyses comparing SAS, AS, and autism across individual SCQ items (excluding participants under 4 years)

From: The behavioural phenotype of SATB2-associated syndrome: a within-group and cross-syndrome analysis

Item number

Item

Number scoring on individual item

Chi-square test

SAS

(n = 55)

AS

(n = 58)

Autism

(n = 60)

χ2 ⁑

p value

Post hoc test

 

Reciprocal social interaction

      

9

Inappropriate facial expressionsb

44

19

26

27.351

< .001

SAS > AS**, aut**

10

Use of other’s body to communicate

50

45

48

3.949

.137

 

19

Friends

27

31

44

8.065

.018

 

26

Eye gazec, d

43

25

37

14.526

.001

SAS > AS**

27

Social smilingc, e

44

15

40

38.013

< .001

SAS**, aut** > AS

28

Showing and directing attentionb, c

44

25

25

20.546

< .001

SAS > AS**, aut**

29

Offering to sharef, g

34

30

49

13.224

.001

aut > SAS*, AS**

30

Seeking to share enjoymentb, c

46

25

34

19.229

< .001

SAS > AS**, aut*

31

Offering comfortf, c

36

31

43

4.931

.088

 

32

Quality of social overturesb, c

48

25

29

26.042

< .001

SAS > AS**, aut**

33

Range of facial expressionsf, c

34

19

47

27.307

< .001

SAS*, aut** > AS

36

Interest in other childrenb, g

39

21

50

30.522

< .001

SAS**, aut** > AS

37

Response to other children’s approachesb, g

41

18

47

32.785

< .001

SAS**, aut** > AS

39

Imaginative play with peersf, c

7

45

54

87.752

< .001

AS**, aut** > SAS

40

Group playb, c

14

38

52

48.159

< .001

aut** > AS > SAS**

 

Communication

      

2a

Conversation

11

-

19

4.373

.061

 

3a

Stereotyped utterances

11

-

39

-

.098

 

4a

Inappropriate questions

6

-

26

1.813

.219

 

5a

Pronoun reversalb

9

-

35

-

.103

 

6a

Neologisms

9

-

34

-

.259

 

20a

Social chatf

8

-

32

-

.080

 

21

Imitationb, c

30

43

48

10.794

.004

aut > SAS*

22

Pointing to express interestf, c

38

33

46

6.147

.047

 

23

Gesturesb, c

43

34

42

4.651

.101

 

24

Nodding to mean yesb, c

27

37

46

10.355

.006

aut > SAS*

25

Head shaking to mean nob, g

34

33

42

2.063

.359

 

34

Imitative social playb, c

25

36

46

12.860

.002

aut > SAS**

35

Imaginative playb, g

24

44

47

21.433

< .001

AS**, aut** > SAS

 

Restrictive, repetitive, and stereotyped behaviour

      

7a

Verbal rituals

12

-

35

-

1.000

 

8

Compulsions and ritualsh, c

38

14

47

39.711

< .001

SAS > AS**, aut** > AS

11

Unusual preoccupations

26

24

43

12.247

.002

aut > AS*

12

Repetitive use of objects

33

48

42

5.659

.060

 

13

Circumscribed interests

34

24

40

8.557

.014

 

14

Unusual sensory interests

27

38

46

9.559

.009

aut > SAS*

15

Hand and finger mannerisms

34

43

52

9.351

.009

aut > SAS*

16

Complex body mannerismsg

21

26

45

17.471

< .001

aut > SAS**, AS*

 

Not in algorithm

      

17

Self-injury

25

28

36

2.781

.250

 

18

Unusual attachment to objects

31

7

31

28.419

< .001

SAS**, aut** > AS

38

Attention to voiceb, c

42

21

45

25.447

< .001

SAS**, aut** > AS

  1. Significant group differences highlighted in bold. Group difference italicised = test statistic approached statistical significance at p = .01 (deemed to approach statistical significance if p = .011 to .014). *Post hoc analysis significant at p < .01, **post hoc analysis significant at p < .001. ⁑ Fisher’s exact test analysis conducted where value is not reported. aItem only calculated for verbal participants (SAS; n = 14, autism; n = 41); Chi-square analyses only calculated for SAS–autism comparisons. bData missing for one participant in autism group. cData missing for one participant in AS group. dData missing for three participants in autism group. eData missing for four participants in autism group. fdata missing for two participants in autism group. gData missing for two participants in AS group. hData missing for one participant in SAS group