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Table 5 Parameter estimates from age-based mixed models (matched trios)

From: Neuropsychological changes in FMR1 premutation carriers and onset of fragile X-associated tremor/ataxia syndrome

 

Estimate (SE)

t-value

Pr > |t|

Visual working memory (SWM errors)

 Intercept

32.37 (5.05)

6.41

<.001

 Age

− 0.087 (0.33)

− 0.26

0.796

 Conv vs. NConv

− 17.90 (6.92)

− 2.59

0.013

 Conv vs. Cont

18.7 (6.98)

2.49

0.011

 ConvSlope vs NConvSlope

1.136 (0.46)

2.50

0.017+

 ConvSlope vs ContSlope

− 0.70 (0.46)

− 1.55

0.128

Motor dexterity (Purdue Pegboard score)

 Intercept

38.97 (1.18)

32.90

<.001

 Age

− 0.24 (0.08)

− 3.16

<.001

 Conv vs. NConv

1.89 (1.64)

1.15

0. 255

 Conv vs. Cont

− 3.37 (1.64)

− 2.06

0.046

 ConvSlope vs NConvSlope

− 0.067 (0.11)

− 0.64

0.528

 ConvSlope vs ContSlope

− 0.036 (0.10)

− 0.34

0.735

Planning (OTS score)

 Intercept

10.52 (0.56)

18.53

<.001

 Age

0.02 (0.04)

0.45

0.654

 Conv vs. NConv

2.52 (0.79)

3.21

0.003

 Conv vs. Cont

− 1.28 (0.78)

− 1.63

0.110

 ConvSlope vs NConvSlope

− 0.15 (0.05)

− 2.94

0.005*

 ConvSlope vs ContSlope

0.10 (0.05)

2.01

0.051+

  1. “Age” = change in value per year of age, centered at youngest age in this matched sample which is 47.9 years. * < .05, + < .10 after Benjamini Hochberg correction for multiple comparisons