Fig. 9
Survey of wheel running phenotypes in young Rcan1 KO, RCAN1 TG, Dp16, and Rcan1 dosage-corrected Dp16 mice. Dual-gradient heatmap depicting the percentage differences of young Rcan1 KO and RCAN1 TG mice relative to young Rcan1 WT and NTG control mice, respectively (left horizontal axis) as well as young Dp16 and Dp16/Rcan12N mice relative to young WT control mice (right horizontal axis) for measures of wheel running patterns and rhythms in light-entrained (LD) and free-running (DD) conditions (vertical axis). A percentage difference of zero indicates no difference (depicted in gray) relative to the corresponding control group, whereas percentage differences of ≤−40% and ≥70% indicate a 40% or greater decrease (depicted in red) and a 70% or greater increase (depicted in green), respectively, relative to the corresponding control group