Skip to main content

Table 2 Differences in SIPS-measured sleep disturbance between groups

From: Copy number variation at the 22q11.2 locus influences prevalence, severity, and psychiatric impact of sleep disturbance

Covariates Effect of time Effect of covariate Effect of subject group Group × time interaction
Cross-sectional β p-value Group β p-value Group β q-value β p-value
 Age + sex - - - 0.198 0.004 Del 0.728 <0.001 - -
    - - - Dup 0.741 <0.001 - -
 Age+ sex + attention - - - 0.222 0.015 Del 0.525 0.009 - -
    -    Dup 0.592 0.014 - -
 Age+ sex + medication - - Antipsychotic 0.557 0.026 Del 0.580 <0.001 - -
    Mood Stabilizer 0.242 0.354 Dup 0.675 <0.001 - -
    Stimulant −0.027 0.932 - - - - -
    Other 0.521 0.107 - - - - -
 Age + sex + IQ - - - −0.128 0.244 Del 0.516 0.026 - -
       Dup 0.500 0.070 - -
 Age + sex + ASD - - - 0.033 0.643 Del 0.782 <0.001 - -
       Dup 0.811 0.001 - -
 Age + sex + PSY - - - 0.558 0.054 Del 0.648 <0.001 - -
       Dup 0.743 <0.001 - -
Longitudinal β p-value Group β p-value Group β q-value β p-value
 Age + sex −0.074 0.754   0.213 <0.001 Del 0.747 <0.001 −0.122 0.601
       Dup 0.747 <0.001 −0.325 0.289
 Age+ sex + attention −0.214 0.276 - 0.222 0.003 Del 0.546 0.005 0.023 0.927
       Dup 0.611 0.010 −0.273 0.421
 Age+ sex + medication −0.074 0.690 Antipsychotic 0.537 0.013 Del 0.600 <0.001 −0.106 0.654
    Mood Stabilizer 0.321 0.109 - - - - -
    Stimulant 0.110 0.657 - - - - -
    Other 0.430 0.099 Dup 0.662 <0.001 −0.363 0.261
 Age + sex + IQa −0.196 0.312 - −0.102 0.299 Del 0.574 0.011 −0.130 0.595
       Dup 0.522 0.056 - -
 Age + sex + ASD −0.061 0.740 - −0.048 0.387 Del 0.669 <0.001 −0.085 0.725
       Dup 0.647 0.005 −0.312 0.314
 Age + sex + PSY −0.055 0.767 - 0.305 0.118 Del 0.703 <0.001 −0.120 0.615
       Dup 0.748 <0.001 −0.381 0.229
  1. aInsufficient longitudinal IQ data in 22q11.2 duplication group