Copy number variation at the 22q11.2 locus influences prevalence, severity, and psychiatric impact of sleep disturbance

Table 4 Results of longitudinal models

	Effect of sleep		Effect of CNV group		Effect of time		Group×time interaction
	β	q-value	β	q-value	β	p-value	β	p-value
Positive symptoms	0.706	<0.001	−0.675	<0.001	−0.207	0.005	0.044	0.750
Total repetitive behaviors	0.521	0.018	0.213	0.307	−0.055	0.694	−0.015	0.957
Social responsiveness	0.546	0.015	0.166	0.418	−0.136	0.216	0.263	0.232
BRIEF global composite	0.425	0.065	0.179	0.394	−0.255	0.042	0.358	0.155
Anxious/depressed	0.619	0.005	−0.305	0.237	−0.200	0.247	0.067	0.840
Withdrawn/depressed	0.355	0.082	−0.328	0.237	−0.348	0.049	0.203	0.543
Somatic complaints	0.461	0.038	−0.511	0.064	−0.266	0.129	0.664	0.047
Social problems	0.362	0.081	−0.270	0.282	−0.194	0.314	−0.020	0.958
Thought problems	1.038	<0.001	−0.490	0.064	0.049	0.763	0.135	0.661
Attention problems	0.421	0.061	−0.202	0.401	−0.253	0.149	0.194	0.560
Rule breaking	0.247	0.195	−0.448	0.101	0.080	0.675	0.009	0.980
Aggressive behavior	0.677	0.002	−0.100	0.624	−0.011	0.947	0.010	0.974

ISSN: 1866-1955