Fig. 1
From: Cortical and subcortical morphological alteration in Angelman syndrome
VBM and SBM analyses in AS-HC cohort showing by T statistic maps (reduced in blue and increased in red). VBM analysis showed significantly decreased gray matter volume in the subcortical nucleus and cerebellum (a) and significantly increased gray matter volume in the (b). The SBM analysis showed significantly reduced CTH (c) and significantly increased LGI across whole-brain in patients with AS when compared with HC (d). The results were thresholded at p < 0.05 in FWE peak correction, and clusters with less than 10 vertexes were eliminated. AS Angelman syndrome, HC health controls, Se seizure, NSe non-seizure, CTH cortical thickness, LGI local gyrification index