Long-term follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder: corpus callosum white matter microstructure and neurocognitive outcomes

Table 1 Diffusion MRI acquisition parameters

Sequence	Imaging parameters
T1 weighted	Multi-echo MP-RAGE sequence with TR = 2500 ms, TE = 1.8/3.6/5.4/7.2 ms, TI = 1000 ms, voxel size = 0.8 mm isotropic, flip angle = 8°
T2 weighted	SPACE sequence with TR = 3200 ms, TE = 564 ms, voxel size = 0.8 mm isotropic, variable flip angle
Diffusion weighted	Multiband EPI sequence with TR = 3230 ms, TE = 89.2 ms, voxel size = 1.5 mm isotropic, MB = 4. Four consecutive runs of about 5:31 each were acquired with 2 shells (b = 1500 and 3000 s/mm²) and 46 directions each and 7 volumes with b = 0 s/mm2.^a

^aFour participants had only 2 diffusion-weighted scans, and in two participants, one of the DWI scans was rerun; all data were included in this analysis
TR Repetition time, TE Echo time, MB Multiband, ms Milliseconds

ISSN: 1866-1955