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Table 3 Treatment group differences in executive function performance at follow-up evaluation

From: Long-term follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder: corpus callosum white matter microstructure and neurocognitive outcomes

Median; mean (SD) {n}

Placebo

Choline

Statistic

Significance

Effect size

WISC-V

 Digit Span

6.0; 6.88 (3.68) {8}

9.0; 8.29 (2.43) {7}

W = 35.5

0.41

0.45

 Picture Span

10.0; 9.29 (2.63) {7}

11.0; 10.14 (4.38) {7}

W = 31.5

0.40

0.23

D-KEFS Trail Making Test

 Visual scanning

9.5; 9.12 (3.60) {8}

10.0; 9.29 (3.90) {7}

W = 32.0

0.68

0.04

 Number sequencing

11.0; 9.88 (3.98) {8}

12.0; 11.57 (0.98) {7}

W = 36.5

0.34

0.58

 Letter sequencing

9.5; 8.50 (5.10) {8}

10.0; 8.0 (4.90) {7}

W = 27.5

1.00

−0.09

 Number/letter sequencing

10.5; 7.0 (3.59) {8}

11.0; 9.14 (3.14) {7}

W = 1.2

0.91

0.61

 Motor speed

10.0; 9.12 (3.18) {8}

12.0; 11.86 (1.21) {7}

W = 45.5

0.04*

1.14

D-KEFS Color-Word Interference Test

 Color naming

3.0; 4.38 (2.92) {8}

10.0; 8.43 (3.41) {7}

W = 45.0

0.05

1.27

 Word reading

8.0; 7.75 (2.05) {8}

9.0; 9.86 (1.68) {7}

W = 42.0

0.11

1.13

 Inhibition

3.5; 5.62 (5.01) {8}

10.0; 8.57 (2.76) {7}

W = 37.5

0.29

0.72

 Inhibition/switching

7.5; 6.88 (4.67) {8}

10.0; 9.71 (2.06) {7}

W = 41.0

0.14

0.78

  1. WISC-V Wechsler Intelligence Scale for Children, 5th Edition, D-KEFS Delis-Kaplan Executive Function System
  2. *Significance p < .05