Fig. 4

Network architecture of psychopathology in XYY syndrome. A Heatmap showing Pearson correlation coefficients between pairs of scales across individuals with XYY syndrome. Scales are grouped according to the optimum k = 8 weighted stochastic block model (WSBM) solution, and black lines define boundaries between blocks defining pairwise correlations between measures within and between each cluster. B Network representation of the WSBM solution shown in (A). Each node is one of the 8 clusters in (A). Edges show the WSBM-estimated mean correlation between scales in each cluster (edge width indexes correlation magnitude: thicker indicates more positive). Node size represents weighted degree based on these edge strengths. Graph layout is with the Fruchterman-Reingold force-directed algorithm. C Heatmap showing correlations (Pearson r) between person-level WSBM cluster scores and variation in IQ (Full-Scale IQ), VABC (Vineland Adaptive Behavior Composite Scale), and CSQ (Caregiver Strain Questionnaire) scores. Asterisk indicates statistical significance at p < 0.005