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Table 1 Demographic, genetic and behavioural data and global volume

From: White matter microstructure in 22q11 deletion syndrome: a pilot diffusion tensor imaging and voxel-based morphometry study of children and adolescents

  22q11DS (n = 11) Controls (n = 12) P-value
Gender male/female 5/6 8/4 1.0, 0.39
Mean Age 12 (SD ± 2.2; Range: 9–17) 13 (SD ± 2.5; Range: 9–17) 0.83
Mean FSIQ 66 (SD ± 8.0; Range: 56–84) 116 (SD ± 15.9; Range: 90–141) <0.001
Handedness 11 Right 12 Right
Strengths and Difficulties Questionnaire mean total score 15.2 (SD ± 7.1; Range: 6–25) 4.9 (SD ± 3.4; Range: 0–11) 0.002
Schizotypy mean score 2.0 (SD ± 2.3; Range: 0–7) 0 (SD ± 0; Range: 0) 0.034
Autism Screening Questionnaire mean score 6.8 (SD ± 4.3; Range: 0–13) 2 (SD ± 4.0; Range: 0–10) 0.044
COMT status 7 VCOMT vs. 4 MCOMT 0.549
Mean global grey matter volume (ml) 738 (SD ± 69.1; Range: 649–814) 790 (SD ± 59.0; Range: 692–896) 0.067
Mean global white matter volume (ml) 385 (SD ± 36.5; Range: 321–436) 418 (SD ± 62.2; Range: 327–512) 0.138
Mean total brain volume (ml) 1122 (SD ± 97.8; Range: 975–1234) 1207 (SD ± 108.3; Range: 1018–1408) 0.062