Table 1 Demographic, genetic and behavioural data and global volume
|  | 22q11DS (n = 11) | Controls (n = 12) | P-value |
|---|---|---|---|
Gender male/female | 5/6 | 8/4 | 1.0, 0.39 |
Mean Age | 12 (SD ± 2.2; Range: 9–17) | 13 (SD ± 2.5; Range: 9–17) | 0.83 |
Mean FSIQ | 66 (SD ± 8.0; Range: 56–84) | 116 (SD ± 15.9; Range: 90–141) | <0.001 |
Handedness | 11 Right | 12 Right | – |
Strengths and Difficulties Questionnaire mean total score | 15.2 (SD ± 7.1; Range: 6–25) | 4.9 (SD ± 3.4; Range: 0–11) | 0.002 |
Schizotypy mean score | 2.0 (SD ± 2.3; Range: 0–7) | 0 (SD ± 0; Range: 0) | 0.034 |
Autism Screening Questionnaire mean score | 6.8 (SD ± 4.3; Range: 0–13) | 2 (SD ± 4.0; Range: 0–10) | 0.044 |
COMT status | 7 VCOMT vs. 4 MCOMT | – | 0.549 |
Mean global grey matter volume (ml) | 738 (SD ± 69.1; Range: 649–814) | 790 (SD ± 59.0; Range: 692–896) | 0.067 |
Mean global white matter volume (ml) | 385 (SD ± 36.5; Range: 321–436) | 418 (SD ± 62.2; Range: 327–512) | 0.138 |
Mean total brain volume (ml) | 1122 (SD ± 97.8; Range: 975–1234) | 1207 (SD ± 108.3; Range: 1018–1408) | 0.062 |